Nicotinamide riboside (a natural form of vitamin B3) is a precursor to NAD +, an activator of sirtuins and a mimetic low calorie diet.
SOURCE NR-NMN GEROPROTECTOR
Nicotinamide riboside, the precursor of NAD +. The body produces energy from ATP, a substance secreted by cellular mitochondria through chemical reactions of the citric acid cycle (or the Krebs cycle) and the electron transport chain. A key component of both processes is nicotinamide adenine dinucleotide (NAD +). It is here that the need arises for nicotinamide riboside. Studies show that nicotinamide riboside, the active ingredient of NOBEL, is the direct precursor of NAD +. An adequate amount of NAD + in the body ensures proper functioning of mitochondria in the cells of the body and leads to an increase in the production of ATP, a source of energy, which positively affects endurance for athletes and the level of energy in people experiencing problems with fatigue. In addition, nicotinamide riboside supports NAD + as a critical substrate for sirtuin enzymes, which plays an important role in ensuring healthy aging processes, weight control and fat metabolism in the liver.
NAD + plays a unique role in aging through DNA repair and epigenetics. With age, there is a decrease in the concentration of NAD + in cells during aging, and stimulation of the production of NAD can prolong life expectancy. Exogenous nicotinamide riboside enhances NAD + biosynthesis and contributes to an increase in life expectancy through two independent paths.
Our cells contain sirtuins (longevity molecules). From their work depends on the restoration of breakdowns in the DNA of our body, and, consequently, the rate of aging. The activity of sirtuins depends on the level of NAD + in the cells of the body.
Interestingly, the level of NAD + increases with low-calorie meals.
SLOWS THE PROCESS OF MEETING AND RESTORES THE STEM CELLS OF MELANOCYTES
It preserves melanocyte stem cells, which are depleted by age and lead to gray hair, NR preserves neural stem cells and slows the graying process.
www.ncbi.nlm.nih.gov/pubmed/27127236
NAD + DNA REPAIR (reconditioned)
NAD + is involved in the mitochondrial metabolic processes of cells.
www.cell.com/abstract/S0092-8674(13)01521-3
www.cell.com/cell-metabolism/abstract/S1550-4131(14)00452-5?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413114004525%3Fshorie%3Dtrue
www.ncbi.nlm.nih.gov/pmc/articles/PMC3616313
REGULATES ELASTICITY OF VESSELS
Affects the propagation of the pulse wave in the arteries, prevents hypertension, cardiovascular events. Reduces oxidative stress. www.ncbi.nlm.nih.gov/pubmed/26970090
Read more: http://young-life.ru/science/nikotinamid-ribozid-nmn