Japanese microbiologist Yoshinori Ohsumi wins Nobel in medicine for autophagy research
Spermidine is an inducer of autophagy. It is a recognized geroprotector, cardioprotector, increases average life expectancy, improves growth and condition of hair.
Increasing food intake with spermidine reduces overall cardiovascular mortality, as well as cancer in humans.
https://www.aging-us.com/article/101517/text
20 YEARS OF RESEARCH PROVED GEROPROTECTIVE PROPERTIES
Scientists of 20 years have watched the 829th participants from Italy. It was found that spermidine is associated with a decrease in mortality and a longer life: the difference in 6 years is between 33% of patients with the highest intake and 33% with the least:
http://www.ncbi.nlm.nih.gov/pubmed/29955838
https://www.aging-us.com/article/101517/text
SPERMYDIN EXTENDS LIFE IN THE COMPOSITION OF FOOD PRODUCTS
Increasing food intake with spermidine reduces overall cardiovascular mortality, as well as cancer in humans.
https://www.aging-us.com/article/101517/text
Read more: http://young-life.ru/science/spermidin/
Naringin / naringinin exhibits pronounced anticarcinogenic activity, suppresses metastases. It is capable of initiating apoptosis of lung cancer cells by activating the expression of a cytokine receptor, namely, tumor necrosis factor (TNF). Interferes with the proliferation of glioma cells, a form of brain cancer, affecting Bcl / Bax apoptosis proteins. Inhibits rectal carcinogenesis and prostate cancer.
Prevents atherosclerosis by lowering cholesterol (LDL). Prevents obesity, metabolic syndrome, insulin resistance, prevents diabetes.
It reduces adipokine, an inflammatory cytokine (for example, tumor necrosis factor TNF-α), which helps to release free fatty acids into the bloodstream and lead to type 2 diabetes.
Anti-inflammatory activity of naringenin allows you to protect the kidneys of sick animals from the development of diabetic nephropathy.
Naringenin suppresses inflammation of the airways in animals with experimentally induced asthma.
Naringenin inhibits the occurrence and spread of inflammation signals in the neuroglia, which helps protect the brain from inflammatory damage leading to degeneration of the nervous tissue.
Naringenin has antibacterial and antiviral activity. The ability of naringenin to inhibit the growth of Staphylococcus aureus (Staphylococcus aureus) resistant to the antibiotic methicillin was detected. Naringenin, can prevent the development of liver infection by the hepatitis C virus – an intractable viral infection affecting 3% of the human population in the world. Studies on hepatocytes have shown that the effectiveness of naringenin in the fight against viral infection is comparable to the effectiveness of interferon, although its mechanism of action is fundamentally different. Naringenin does not affect the production of viral proteins in the cell, but prevents the assembly of viral particles.
Read more: http://young-life.ru/science/naringin/